I find the BMW Sports panniers fine for touring with. I don't like them to be extended as it makes the bike wider for filtering but the ability to "over fill" them then squash them down on the ratchets is great.
I hate top boxes. The worst place to add weight or air resistance on a bike is high behind the rear axle. Exactly where a top box goes. I have a small 5ltr tail pack on my rack for waterproofs, phone etc. when commuting and I don't even like that.
The best way to carry luggage is in a tank bag. the weight is forward and it sits in relatively still air. A well designed and filled tank bag will not only give you somewhere for you luggage but will also give you somewhere to rest your chest and take some weight off your arms after either a lot of town work or a long high speed dash. It also gives easy access for passport, cash, credit card, tickets etc. making toll stops as quick and easy as possible.